Project: ‘New tools and applications of NMR spectroscopy beyond resolution limitation.’
Project coordinator: prof. Wiktor Koźmiński.
Project duration: 2016 - 2021.
Positions for MSc students and Postdoc available.
The aim of the project is an expansion of capabilities of the high-resolution nuclear magnetic resonance (NMR) spectroscopy which is a fundamental tool of modern structural biology. The structure and dynamics of proteins will be studied using new spectral parameters, such as cross-correlated relaxation rates. The research conducted in the frames of the project will make use of multidimensional NMR spectroscopy of isotopically enriched samples (13C, 15N, 2H) of proteins, both of folded and disordered nature. In addition, high hydrostatic pressure NMR will be employed to study conformational equilibria and dynamics of investigated proteins. Exceptionally high-resolution of 4 and 5 dimensional spectra will be achieved thanks to non-uniform sampling and advanced processing tools.
All positions are available from June, 2016. Candidate for MSc position shoud hold BSc preferably in chemistry, physics, biology or computer-science. All stipends are funded from NCN MAESTRO grant.
Postdoc candidates are asked to directly contact project coordinator.
More info: prof. Wiktor Koźmiński,
Application deadline: ongoing recruitment.